Substrate: Protein numb homolog (protein binding)
Seq-ID: P16554 [Drosophila melanogaster]
Download:fasta csv
Interaction Network(s): STRING  
External Source(s): Phosida
MINT Interaction(s):
[show]
MINT-30324   MAD_DROME
MINT-4298316   KPCZ_HUMAN
MINT-4298329   KPCA_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
ATP binding,
Notch binding		 basal cortex,
nucleus		 muscle cell fate specification,
negative regulation of Notch signaling pathway,
asymmetric neuroblast division,
regulation of neurogenesis,
sensory organ precursor cell fate determination,
positive regulation of endocytosis,
glial cell migration,
peripheral nervous system development,
sensory organ precursor cell division,
Notch signaling pathway,
regulation of asymmetric cell division,
ventral cord development,
pericardial cell differentiation,
rhythmic behavior,
neuroblast fate determination,
protein localization
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
T 430 AQVTPRVASTTPTYQTLHSQS - 18327897
HTP
0.14
 - -
0.75
 - medium
T 430 AQVTPRVASTTPTYQTLHSQS - 18327897
HTP
0.14
 - -
0.75
 - medium
S 537 STARSPLARHSTNPFISPPKA - 18327897
HTP
1.00
 - -
0.78
 - medium
S 537 STARSPLARHSTNPFISPPKA - 18327897
HTP
1.00
 - -
0.78
 - medium
S 543 LARHSTNPFISPPKAPAQSFQ - 18327897
HTP
1.00
 - -
0.69
 - medium
S 543 LARHSTNPFISPPKAPAQSFQ - 18327897
HTP
1.00
 - -
0.69
 - medium

Substrate: Protein numb homolog (protein binding)
Seq-ID: P49757 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-17947   EPS15_HUMAN
MINT-74593   EGFR_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
integral to plasma membrane neuroblast division in the subventricular zone,
lateral ventricle development
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
T 102 ADGLRVVDEKTKDLIVDQTIE AAK1 18657069
LTP
1.00
 - PTB
0.26
 --
S 240 VAPGNTAPSPSSPTSPTSDAT - 18669648
HTP
0.15
 - -
0.91
 --
S 241 APGNTAPSPSSPTSPTSDATT - 18669648
HTP
0.10
 - -
0.91
 --
S 244 NTAPSPSSPTSPTSDATTSLE - 18669648
HTP
0.89
 - -
0.91
 --
S 276 APIEQLARQGSFRGFPALSQK - 17609107
LTP
1.00
 - NumbF
0.58
 --
S 295 QKMSPFKRQLSLRINELPSTM - 17609107
LTP
1.00
 - NumbF
0.60
 --
T 436 PGLFQAGHRRTPSEADRWLEE - 18669648
HTP
1.00
 - -
0.68
 --
S 438 LFQAGHRRTPSEADRWLEEVS - 17081983
HTP
1.00
 - -
0.71
 --
S 634 ENKSKQRTNPSPTNPFSSDLQ - 16964243
HTP
1.00
 - -
0.86
 --
S 634 ENKSKQRTNPSPTNPFSSDLQ - 18669648
HTP
1.00
 - -
0.86
 --

Substrate: Protein numb homolog (protein binding)
Seq-ID: Q3MUI1 [Rattus norvegicus]
Download:fasta csv
Interaction Network(s):
External Source(s): Phosida
MINT Interaction(s):-
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
protein binding apical part of cell positive regulation of dendrite morphogenesis,
cell proliferation
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 264 APIEQLARQGSFRGFPALSQK CaM-KI_group 16105844
LTP
1.00
 - NumbF
0.58
 - low
S 264 APIEQLARQGSFRGFPALSQK CaM-KI_group 17022975
LTP
1.00
 - NumbF
0.58
 - low
T 304 QRKTDFPIKNTVPEVEGEAES - 17022975
LTP
0.66
 - NumbF
0.73
 - low

Substrate: Protein numb homolog (protein binding)
Seq-ID: Q9QZS3 [Mus musculus]
Download:fasta csv
Interaction Network(s): STRING  
External Source(s): PhosidaPhosida
MINT Interaction(s):
[show]
MINT-18945   A4_MOUSE
MINT-45917   ITB2_HUMAN
MINT-45920   ITB7_HUMAN
MINT-61569   ITB3_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
cadherin binding,
alpha-catenin binding,
beta-catenin binding		 early endosome,
basolateral plasma membrane,
apical part of cell,
nucleus,
extrinsic to plasma membrane		 positive regulation of neurogenesis,
neuroblast division in the subventricular zone,
adherens junction organization,
axonogenesis,
lateral ventricle development
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
T 243 GNTAPSPSSPTSPTPDGTASS - 19144319
HTP
0.10
 - -
0.95
 - low
T 633 AALESKSKQRTNPSPTNPFSS - 17242355
HTP
0.23
 - -
0.83
 - low
S 636 ESKSKQRTNPSPTNPFSSDLQ - 17242355
HTP
1.00
 - -
0.86
 - low

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